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Biovorin Injection (Calcium Leucovorin) 50 mg/5 ml product image 1
Blood Health

Biovorin Injection (Calcium Leucovorin) 50 mg/5 ml

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$39.00For 1 Injection

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SKU EM-BIOVORIN-D1A3-1INJ

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Biovorin Injection (Calcium Leucovorin) 50 mg/5 ml—
$39.00

Buy Biovorin (Calcium Leucovorin) 50 mg injection online at Essential meds. Available in 5 options. Choose an option to see its price, and review the full details on the product page before ordering.

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Product details

Overview, use & safety

Additional details

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Review the available overview, use, safety, and other product details.

6 sections
Overview

Biovorin Injection contains Calcium Leucovorin, a folinic acid used to reduce the toxic effects of certain chemotherapy drugs like methotrexate. It is also used in combination with 5-fluorouracil (5-FU) to enhance anticancer effects. Calcium Leucovorin acts as a chemoprotectant and is vital in rescue therapy during high-dose methotrexate treatments, helping protect healthy cells without reducing the effectiveness of chemotherapy.

Key Benefits
  • Reduces toxicity from high-dose methotrexate
  • Enhances effectiveness of 5-fluorouracil in cancer treatment
  • Acts as a folate supplement in certain anemias
  • Supports recovery of healthy cells during chemotherapy
How to Use

Biovorin Injection is administered by a healthcare professional, typically by intravenous (IV) or intramuscular (IM) injection. The dose and frequency depend on the indication, methotrexate levels, and patient condition.

Dosage Information
  • Dose varies widely based on therapeutic use (e.g., methotrexate rescue, 5-FU combination)
  • In methotrexate rescue: usually starts 24 hours after methotrexate administration
  • Administered every 6 hours or as prescribed, with careful monitoring of methotrexate plasma levels
  • Only to be used under the supervision of a qualified healthcare provider
Safety Information
  • Not for use in patients with known hypersensitivity to folinic acid or its components
  • Caution in patients with seizure disorders or vitamin B12 deficiency
  • Monitor kidney and liver function during treatment
  • May interact with certain antibiotics and antiepileptics—inform your doctor of all ongoing medications
  • Not a suitable substitute for folic acid in megaloblastic anemia caused by vitamin B12 deficiency
Possible Side Effects
  • Common side effects may include:
  • Injection site reactions (pain, redness)
  • Nausea or vomiting
  • Fatigue
  • Allergic reactions (rash, swelling, difficulty breathing)
  • Seizures in patients with underlying neurological conditions
  • Seek immediate medical attention in case of severe reactions.
  • Rare but serious side effects:

Follow the product label and the advice of a qualified healthcare professional for product-specific use and safety questions.

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