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Neurology & CNS Care

Modafinil Tablets

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$140.00For 100 tablets · 50 mg strength

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SKU EM-MODAFINI-60A6-100TAB50MG

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Modafinil Tablets
$140.00

Modafinil is a prescription-grade wakefulness-promoting agent (eugeroic) widely used to treat excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnoea, and shift work sleep disorder.

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Unlike traditional stimulants, Modafinil promotes alertness without causing significant increases in heart rate or blood pressure, and carries a low potential for dependence. Available in four clinical doses — 50 mg, 100 mg, 200 mg, and 400 mg — this product allows precise dose titration as directed by your physician. Pack sizes of 100 to 400 tablets are available for both short-term and extended treatment. Key Benefits: ✔ Promotes sustained wakefulness and mental alertness ✔ Enhances cognitive function, focus, and concentration ✔ Low abuse potential compared to traditional stimulants ✔ Does not significantly affect normal sleep architecture ✔ Four dose strengths for personalised therapy ✔ Bulk pack options for long-term treatment

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Questions about Modafinil Tablets

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Overview, use & safety

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How It Works

Modafinil's exact mechanism is not fully understood, but it is believed to work primarily by inhibiting the reuptake of dopamine in the brain — increasing dopamine availability in synapses. It also influences norepinephrine, serotonin, histamine, and orexin (hypocretin) systems that regulate wakefulness and sleep-wake cycles. Unlike amphetamines, Modafinil does not cause widespread dopamine release, which explains its lower addiction potential and milder side effect profile. It promotes wakefulness by activating the hypothalamic wake-promoting regions while not suppressing REM sleep in the same way as traditional stimulants.

Dosage & Administration

Always follow your doctor's prescription. General clinical guidelines: Narcolepsy & Sleep Apnoea: - Standard dose: 200 mg once daily in the morning - Some patients may require 400 mg (split or single dose) Shift Work Sleep Disorder: - 200 mg taken approximately 1 hour before the start of the work shift Dose titration: - 50 mg or 100 mg may be used as starting doses to assess tolerance - Dose adjustments should only be made under medical supervision Important: - Take with or without food (food may delay onset by ~1 hour) - Avoid taking in the afternoon or evening to prevent insomnia - Do not crush or split unless advised by your doctor - Swallow whole with a full glass of water

Side Effects

Modafinil is generally well-tolerated. Common and rare side effects include: Common (may affect up to 1 in 10): - Headache (most frequent) - Nausea, dry mouth, loss of appetite - Insomnia or difficulty sleeping if taken late in the day - Nervousness or anxiety - Dizziness Less Common: - Palpitations, elevated blood pressure - Gastrointestinal upset, diarrhoea - Back pain Rare but Serious — stop medication and seek immediate care: - Severe skin reactions: Stevens-Johnson Syndrome, toxic epidermal necrolysis (rash, blistering, peeling skin) - Serious allergic reaction: facial swelling, difficulty breathing - Psychiatric symptoms: hallucinations, agitation, depression, mania (particularly in patients with pre-existing conditions) Report any unusual mood changes, skin reactions, or chest pain to your doctor immediately.

Precautions & Warnings

Controlled substance: Modafinil is a Schedule IV controlled substance in the USA. It requires a valid prescription and should be stored securely. Cardiovascular conditions: Use with caution in patients with a history of heart disease, hypertension, arrhythmia, or left ventricular hypertrophy. Regular BP monitoring is recommended. Psychiatric history: Use with caution in patients with anxiety disorders, psychosis, bipolar disorder, or history of substance abuse. Pregnancy & Breastfeeding: Not recommended. Modafinil may reduce the effectiveness of hormonal contraceptives — use alternative or additional contraception during treatment and for 2 months after. Liver & Kidney impairment: Dose reduction required in severe hepatic impairment. Use with caution in renal impairment. Drug interactions: May reduce effectiveness of oral contraceptives, cyclosporine, and certain HIV medications. May interact with CYP3A4 substrates. Inform your doctor of all medications. Dependence & Withdrawal: Although lower than amphetamines, psychological dependence is possible with prolonged high-dose use. Do not stop abruptly without medical guidance. Driving & machinery: Modafinil may improve wakefulness but underlying sleepiness may still impair driving. Follow your doctor's advice before driving.

Follow the product label and the advice of a qualified healthcare professional for product-specific use and safety questions.

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