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Nublexa 40 mg Tablets (Regorafenib) product image 1
Cancer Care

Nublexa 40 mg Tablets (Regorafenib)

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$2,449.00For 30 tablets

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SKU EM-NUBLEXA4-7999-30TAB

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Nublexa 40 mg Tablets (Regorafenib)—
$2,449.00

Buy Nublexa (Regorafenib) 40 mg tablets online at Essential meds. Available in 5 pack sizes. Choose an option to see its price, and review the full details on the product page before ordering.

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Product details

Overview, use & safety

Additional details

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Review the available overview, use, safety, and other product details.

6 sections
Overview

Nublexa 40 mg contains Regorafenib, a multikinase inhibitor used in the treatment of advanced cancers, including metastatic colorectal cancer (mCRC), gastrointestinal stromal tumors (GIST), and hepatocellular carcinoma (HCC). It works by blocking multiple enzymes (kinases) that promote cancer cell growth and blood supply to tumors, thereby inhibiting tumor progression.

Key Benefits
  • Effective in managing metastatic colorectal cancer after standard therapies
  • Treats advanced gastrointestinal stromal tumors resistant to imatinib and sunitinib
  • Helps control advanced liver cancer (HCC) in patients previously treated with sorafenib
  • Targets multiple pathways involved in tumor growth and angiogenesis
  • Oral formulation for convenient administration
How to Use
  • Take orally once daily with a low-fat meal
  • Swallow the tablet whole with water—do not crush or chew
  • Take at the same time each day
  • Treatment cycles usually follow a 3 weeks on / 1 week off regimen, or as directed by the oncologist
Dosage Information
  • Active Ingredient: Regorafenib 40 mg
  • Typical Adult Dose: 160 mg once daily for the first 21 days of each 28-day cycle
  • Dose adjustments may be necessary based on tolerance and liver function
  • Do not exceed the prescribed dosage
Safety Information
  • Not recommended during pregnancy or breastfeeding
  • Monitor liver function tests before and during treatment
  • Use caution in patients with hypertension, heart disease, or bleeding disorders
  • Regular monitoring of blood pressure, CBC, and liver enzymes is advised
  • Avoid grapefruit and its juice, which may increase drug levels
Possible Side Effects
  • Common Side Effects:
  • Fatigue
  • Diarrhea
  • Loss of appetite
  • Hand-foot skin reaction (HFSR)
  • Serious Side Effects:
  • Liver toxicity
  • Severe bleeding
  • Heart problems
  • Gastrointestinal perforation
  • Seek immediate medical attention if you experience chest pain, yellowing of eyes/skin, or black/tarry stools.
  • High blood pressure

Follow the product label and the advice of a qualified healthcare professional for product-specific use and safety questions.

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